Designed for aseptic fluid handling in pharmaceutical, biotechnology and laboratory applications, these filling and venting closures feature pre-mounted lengths of platinum cured silicone tubing, a platinum cured silicone gasket and a polypropylene (PP) cap and adapter with molded-in hose barbs that accept additional fluid transfer components such as aseptic connectors and air vent filters. Caps are compatible on bottles and carboys with 53 mm, 83 mm or 120 mm closures and all components can be autoclaved at 15 psi and 250 deg F for 20 min.